| Applera Corporation-Celera Genomics Group (ABI)
|" Applera Corporation-Celera Genomics Group " Graph source Edgar Online Pro on April 21st, 2006
The Following data is sourced from Yahoo Finance & the ANNUAL REPORT ON FORM 10-K For the fiscal year ended June 30, 2005 The overview of the company was:
Applera Corp-Applied Biosystems Group (ABI) engages in the development and marketing of instrument-based systems, consumables, software, and services. It develops technologies and products to support applications in genomics research, such as sequencing, genotyping, and gene expression studies. The company’s products and services are used in analyze nucleic acids, such as DNA and RNA; small molecules; and proteins to make scientific discoveries, develop new pharmaceuticals, and conduct standardized testing. It offers various software products for laboratory information management systems. These products are designed to facilitate sample tracking, data collection, data analysis, and data mining. The company markets its products to life sciences industry and research community, including basic human disease research and genetic analysis performed by universities, government agencies, and other nonprofit organizations; pharmaceutical drug discovery, development, and manufacturing; agriculture research; forensic testing and human identification; biosecurit, which refers to products needed in response to the threat of biological terrorism and other malicious, accidental, and natural biological dangers; and food and environmental testing. The company was founded in 1937 and is headquartered in Foster City, California.
Applera Corporation-Celera Genomics Group (CRA),principally engages in the discovery and development of targeted therapeutics for cancer, autoimmune, and inflammatory diseases in the United States. It leverages its proteomic, bioinformatic, and genomic capabilities to identify and validate drug targets, and to discover and develop small molecule therapeutics. The company has strategic collaborations with Abbott Laboratories to discover, develop, and commercialize targeted therapies for cancer; with General Electric Company to accelerate the discovery and development of new products for personalized, or targeted, medicine; and with Seattle Genetics, Inc. to discover, develop, and commercialize antibody-based therapies for cancer. Applera Corporation-Celera Genomics is headquartered in Norwalk, Connecticut. Applera Corporation-Celera Genomics Group is a division of Applera Corporation.
Highlights of Risks Related to Our (ABI) Business
For further detail please review the 10 K Form in detail.
I. Factors Relating to Applied Biosystems
1. Rapidly changing technology in life sciences could make Applied Biosystems’ product line obsolete unless it continues to develop and manufacture new and improved products and services, and pursue new market opportunities.
2. Applied Biosystems relies on third parties for the manufacture of some of its products and also for the supply of some components of the products it manufactures on its own.
3. A significant portion of sales depends on customers’ capital spending policies that may be subject to significant and unexpected decreases.
4. A substantial portion of Applied Biosystems ’ sales is to customers at universities or research laboratories whose funding is dependent on both the amount and timing of funding from government sources.
5. Applied Biosystems is currently, and could in the future be, subject to lawsuits, arbitrations, investigations, and other legal actions with private parties and governmental entities, particularly involving claims for infringement of patents and other intellectual property rights, and it may need to obtain licenses to intellectual property from others.
6. Since Applied Biosystems’ business is dependent on foreign sales, fluctuating currencies will make revenues and operating results more volatile.
7. The future growth of Applied Biosystems depends in part on its ability to acquire complementary technologies through acquisitions, investments, or other strategic relationships or alliances, which may absorb significant resources, may be unsuccessful, and could dilute holders of Applera-Applied Biosystems stock.
8. Applied Biosystems’ businesses, particularly those focused on developing and marketing information-based products and services, depend on the continuous, effective, reliable, and secure operation of its computer hardware, software, and Internet applications and related tools and functions.
9. Applied Biosystems’ operations involve the use, manufacture, sale, and distribution of hazardous materials, and the mishandling of these hazardous materials could result in substantial liabilities and harm to Applied Biosystems.
10. Earthquakes could disrupt operations in California.
11. Applera-Applied Biosystems stock price may be volatile.
II. Factors Relating to Celera Genomics :
1. Celera Genomics has incurred net losses to date and may not achieve profitability. .
2. The marketing and distribution agreement with Applied Biosystems may not generate significant royalty payments.
3. Celera Genomics’ ability to develop and commercialize proprietary therapeutic products is unproven and several of its programs rely on the use of novel discovery methods.
4. For some of Celera Genomics’ research and product development programs, particularly its proteomics efforts, Celera Genomics needs access to human and other tissue samples from diseased and healthy individuals, other biological materials, and related clinical and other information, which may be in limited supply.
5. Therapeutic product candidates may never result in a commercialized product.
6. If Celera Genomics fails to maintain its existing collaborative relationships and enter into new collaborative relationships, or if collaborators do not perform under collaboration agreements, development of its therapeutic product candidates could be delayed.
7. If Celera Genomics or its collaborators fail to satisfy regulatory requirements for any therapeutic product candidate, Celera Genomics or its collaborators will be unable to complete the development and commercialization of that product.
8. Clinical trials may not be successful.
9. Clinical trials may take several years or more and can be very expensive.
10. Celera Genomics relies on other companies to conduct clinical trials.
11. Celera Genomics’ relies on suppliers for materials needed to manufacture compounds for clinical trials.
12. Celera Genomics relies on other companies to manufacture its therapeutic product candidates.
13. Celera Genomics' collaborations with outside experts may be subject to restriction and change.
14. The pharmaceutical industry is intensely competitive and evolving.
15. Introduction of new products may expose Celera Genomics to product liability claims.
16. Therapeutics discovery and development is a highly technical field and there is a competitive market for personnel with the expertise needed for the expansion of Celera Genomics’ business operations within this field.
17. Celera Genomics could incur liabilities relating to hazardous materials that it uses in its research and development activities.
18. Celera Genomics’ business depends on the continuous, effective, reliable, and secure operation of its computer hardware, software, and Internet applications and related tools and functions.
19. Celera Genomics’ competitive position depends on maintaining its intellectual property protection.
20. Celera Genomics may infringe the intellectual property rights of third parties, may become involved in expensive intellectual property legal proceedings, and may need to obtain licenses to intellectual property from others.
21. Ethical, legal, and social issues related to the use of genetic information and genetic testing may cause less demand for Celera Genomics’ products.
22. Celera Genomics may pursue acquisitions, investments, or other strategic relationships or alliances, which may consume significant resources, may be unsuccessful, and could dilute the holders of Applera-Celera Genomics stock.
23. Earthquakes could disrupt operations in California .
24. Applera-Celera Genomics stock price may be volatile.
25. Our company is subject to a class action lawsuit relating to its 2000 offering of shares of Applera-Celera Genomics stock that may be expensive and time consuming.
III. Factors Relating to Celera Diagnostics, a 50/50 Joint Venture between Applied Biosystems and Celera Genomics.
1. Celera Diagnostics’ ability to develop and commercialize proprietary diagnostic products is unproven.
2. Diagnostic product candidates may never result in a commercialized product.
3. If Celera Diagnostics or its collaborators fail to satisfy regulatory requirements for any diagnostic product candidate, they may be unable to complete the development and commercialization of that product.
4. Celera Diagnostics’ products may not be fully accepted by physicians and laboratories.
5. Ethical, legal, and social issues related to the use of genetic information and genetic testing may cause less demand for Celera Diagnostics’ products.
6. If insurance companies and other third-party payors do not reimburse doctors and patients for Celera Diagnostics’ tests, its ability to sell its products to the clinical diagnostics market will be impaired.
7. If Celera Diagnostics fails to maintain its existing collaborative relationships and enter into new collaborative relationships, or if collaborators do not perform under collaboration agreements, development of its diagnostic products could be delayed.
8. Celera Diagnostics does not have a sales and service capability in the clinical diagnostic market.
9. Celera Diagnostics has limited manufacturing capability and may encounter difficulties expanding Celera Diagnostics’ operations.
10. Celera Diagnostics’ research and product development depends on access to tissue and blood samples from diseased and healthy individuals, other biological materials, and related clinical and other information, which may be in limited supply.
11. Single suppliers or a limited number of suppliers provide key components of Celera Diagnostics’ products. If these suppliers fail to supply these components, Celera Diagnostics may be unable to satisfy product demand.
12. Celera Diagnostics’ operations involve the use, manufacture, sale, and distribution of hazardous materials, and the mishandling of these hazardous materials could result in substantial liabilities and harm to Celera Diagnostics.
13. Celera Diagnostics’ business depends on the continuous, effective, reliable, and secure operation of its computer hardware, software, and Internet applications and related tools and functions.
14. Celera Diagnostics’ competitive position depends on maintaining its intellectual property protection.
15. Celera Diagnostics may infringe the intellectual property rights of third parties, may become involved in expensive intellectual property legal proceedings, and may need to obtain licenses to intellectual property from others.
16. Introduction of new products may expose Celera Diagnostics to product liability claims.
17. The diagnostics industry is intensely competitive and evolving.
18. Earthquakes could disrupt operations in California.
IV. Risks Relating to a Capital Structure with Two Separate Classes of Common Stock
1. Stockholders of Applera Corporation are stockholders of one company and, therefore, financial effects on one group could adversely affect the other.
2. The market price of either class of our common stock may not reflect the separate performance of the group related to that common stock.
3. The market price of either class of our common stock may be affected by factors that do not affect traditional common stock.
4. Limits exist on the voting power of group common stock.
5. Stockholders may not have any remedies for breach of fiduciary duties if any action by directors or officers has a disadvantageous effect on either class of common stock.
6. Stock ownership could cause directors and officers to favor one group over the other.
7. Numerous potential conflicts of interest exist between the classes of common stock that may be difficult to resolve by our Board of Directors or that may be resolved adversely to one of the classes.
8. Our Board of Directors may change its management and allocation policies without stockholder approval to the detriment of either group.
9. Either Applied Biosystems or Celera Genomics may finance the other group on terms unfavorable to either group.
10. Celera Genomics could incur a higher tax liability than if it were a stand-alone taxpayer.
11. Holders of group common stock may receive less consideration upon a sale of assets than if the group were a separate company.
12. Our capital structure and variable vote per share may discourage acquisitions of a group or a class of common stock.
13. Decisions by our Board of Directors and officers that affect market values could adversely affect voting and conversion rights.
14. Provisions governing common stock could discourage a change of control and the payment of a premium for stockholders’ shares.
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